ANTI-CERAMIDE ANTIBODY AND SPHINGOSINE-1-PHOSPHATE AS POTENTIAL BIOMARKERS OF UNRESECTABLE NON-SMALL CELL LUNG CANCER

Anti-ceramide antibody and sphingosine-1-phosphate as potential biomarkers of unresectable non-small cell lung cancer

ObjectivesSpingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate.Anti-ceramide antibodies might inhibit the effects of ceramide.The aim of this study was to assess the potential role of circulating S1P and anti-ceramide antibody as biomarkers in non-small cell lung cancer (NSCLC).MethodsWe recruited 6

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Vivências do Lazer para Discentes do Curso de Educação Física da Universidade Federal do Pará no Contexto de Pandemia da Covid – 19

O estudo objetiva analisar as vivências de lazer de discentes do curso de 5" Squares (Charm Packs) Educação Física da Universidade Federal do Pará, no contexto da pandemia da COVID-19.A metodologia da pesquisa é descritiva e de abordagem quali-quantitativa.O instrumento foi um questionário produzido e enviado via Google Forms.Participaram da

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Cost-effectiveness analysis of abiraterone, docetaxel or placebo plus androgen deprivation therapy for hormone-sensitive advanced prostate cancer

ABSTRACT Objective To evaluate the cost-effectiveness of the addition of chemotherapy or abiraterone to androgen deprivation.Methods We developed an All Purpose Cleaners analytical model to determine the cost-effectiveness of the addition of docetaxel or abiraterone versus androgen deprivation therapy alone.Direct and indirect costs were included i

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